|
KMID : 1022420100020020101
|
|
Phonetics and Speech Sciences
2010 Volume.2 No. 2 p.101 ~ p.108
|
|
|
A Study about Voice of Patients with Chronic Obstructive Pulmonary Disease/Asthma before & after β₂-agonist
|
|
Kang Young-Ae
Kim Se-Hun
Jung Seong-Su
Lee Tae-Yong
Seong Cheol-Jae
|
|
|
Abstract
|
|
|
|
An inhaled salbutamol and salmeterol for chronic obstructive pulmonary disease(COPD) and asthma have been used worldwidely. But there has been few study about the voice change evoked from the post-medicine effect. To evaluate the voice influenced of short-acting and long-acting β₂-agonists, two experiments were carried out: one was salbutamol experiment 1 with eight patients, the other was salmeterol experiment 2 with six patients. Experiment 1 was made of two stages: premedication & postmedication. Experiment 2 was four stages: stageI was premedication, stageⅡ was postmedication & pregaggling, stageⅢ was postmedication & postgaggling(100 ml with water), and stageⅣ was postmedication & 30 minutes later. Measured parameters were F0, F0_SD, Jitter_rap, Shimmer_apq11, HNR, BW(1, 2, 3), Intensity, and H1-H2. The mean data collected from 3 repetitions each was statistically analyzed by Wilcoxon signed rank test for experiment 1 and repeated measures ANOVA for experiment 2. In experiment 1, significant differences were found in the Jitter_rap(Z= -2.10, p=0.036). The findings indicated that the postmedicated voice was worse than premedicated voice. In experiment 2, there wasn"t significant difference, but values of parameters related to voice quality(Jitter_rap, Shimmer_apq11, HNR, and H1-H2) showed changes toward stageⅣ, that is, the voice quality was worse under medication.
|
|
|
KEYWORD
|
|
|
Voice, COPD, asthma, salbutamol, salmeterol
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
|
|